Heart failure ALDOSTERONE BLOCKADE IN CARDIOVASCULAR DISEASE
نویسنده
چکیده
Correspondence to: Professor Allan D Struthers, Division of Medicine & Therapeutics, Ninewells Hospital & Medical School, Dundee, DD1 9SY, UK; [email protected] _________________________ I t was once thought that aldosterone was a hormone released purely from the adrenal cortex, which circulated in the bloodstream and acted only on the kidneys to retain sodium and excrete potassium. This is now recognised to be a gross oversimplification (table 1).
منابع مشابه
Clinical Medicine Insights: Therapeutics
Aldosterone blockade has been shown to be effective in reducing total mortality in patients with severe heart failure due to systolic left ventricular dysfunction and in patients with heart failure post myocardial infarction. Increasing evidence suggests that aldosterone blockade alone and or in conjunction with an angiotensin converting enzyme inhibitor (ACE-I) or angiotensin receptor blocker ...
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